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MD students

MD students

Julian Alecu

MD student

Department of Stem Cell Biology
AG Winner

Supervisor

Project Title: Reducing α-synuclein oligomers as an approach to rescue cell death of iPSC-derived midbrain neurons from patients with Parkinson’s disease

Publications:

Brazdis RM, Alecu J, Marsch D, Dahms A, Simmnacher K, Lorentz S, Brendler A, Schneider Y, Marxreiter F, Roybon L, Winner B, Xiang W, Prots I (2020) Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease. Hum Mol Genet pii: ddaa039. doi: 10.1093/hmg/ddaa039

Monica Bieg

MD student

Department of Molecular Neurology
Prof. Winkler

Supervisor

Project Title: Activation of myeloid cells in a transgenic mouse model of Huntington’s Disease

Katharina Braun

MD student

Institute of Biochemistry
Prof. Chichung Lie

Supervisor

Project Title: Role of the intellectual disability and schizophrenia associated transcription factor TCF4 in adult neurogenesis of hippocampal dentate gyrus

Anna Brendler

MD student

Department of Stem Cell Biology
Prof. Beate Winner

Supervisor

Project Title: Distinct role of T cell subcells in alpha-synuclein aggregation

Publications:

Brazdis RM, Alecu J, Marsch D, Dahms A, Simmnacher K, Lorentz S, Brendler A, Schneider Y, Marxreiter F, Roybon L, Winner B, Xiang W, Prots I (2020) Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease. Hum Mol Genet pii: ddaa039. doi: 10.1093/hmg/ddaa039

Razvan-Marius Brazdis

MD student

Department of Stem Cell Biology
AG Winner

Supervisor

Project Title: The impact of α –Synuclein gene duplication on motor adaptor proteins of anterograde mitochondrial transport

Publications:

Brazdis RM, Alecu J, Marsch D, Dahms A, Simmnacher K, Lorentz S, Brendler A, Schneider Y, Marxreiter F, Roybon L, Winner B, Xiang W, Prots I (2020) Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease. Hum Mol Genet pii: ddaa039. doi: 10.1093/hmg/ddaa039

Prots I, Grosch J, Brazdis RM, Simmnacher K, Veber V, Havlicek S, Hannappel C, Krach F, Krumbiegel M, Schütz O, Reis A, Wrasidlo W, Galasko DR, Groemer TW, Masliah E, Schlötzer-Schrehardt U, Xiang W, Winkler J, Winner B. α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7813-7818. doi: 10.1073/pnas.1713129115. Epub 2018 Jul 10.

Christian Fiebig

MD student

Institute of Biochemistry
AG Beckervordersandforth

Supervisor

Project Title: The Impact of ageing and neurodegeneration on mitochondrial morphology in hippocampal stem cells

Publications:

Fiebig, C., Keiner, S., Ebert, B., Schaffner, I., Jagasia, R., Lie, D. C. & Beckervordersandforth, R. 2019. Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion. Front Mol Neurosci, 12, 40.

Beckervordersandforth, R., Ebert, B., Schaffner, I., Moss, J., Fiebig, C., Shin, J., Moore, D. L., Ghosh, L., Trinchero, M. F., Stockburger, C., Friedland, K., Steib, K., Von Wittgenstein, J., Keiner, S., Redecker, C., Holter, S. M., Xiang, W., Wurst, W., Jagasia, R., Schinder, A. F., Ming, G. L., Toni, N., Jessberger, S., Song, H. & Lie, D. C. 2017. Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis. Neuron, 93, 560-573 e6.

Fabienne Grolig

MD student

Institute of Biochemistry
AG Lie

Supervisor

Project Title: Investigating the role of FoxO transcription factors in the maintenance of mitochondrial homeostasis in adult neural stem/progenitor cells

Lara Hammad

MD student

Department of Molecular Neurology
Prof. Winkler

Supervisor

Project Title: The serotonergic innervation of the hippocampus in a transgenic ASM model

Publications:

Kalinichenko LS, Hammad L, Reichel M, Kohl Z, Gulbins E, Kornhuber J, Müller CP. Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice.Brain Res Bull. 2019 Mar;146:310-319. doi: 10.1016/j.brainresbull.2019.01.026. Epub 2019 Feb 1.

Felicia Himmelsbach

MD student

Department of Stem Cell Biology
AG Winner

Supervisor

Project Title: α-synuclein expression and its regulation in lymphocyte subsets

Verena Hundrup

MD student

Lehrstuhl für Psychiatrie und Psychotherapie
AG Fejtová

Supervisor

Project Title: Functional maturation of neuronal networks in Noonan Syndrome

Julian Karpf

MD student

Insitute of Biochemisty
AG Beckervordersandforth

Supervisor

Project Title: Astrocyte heterogeneity in the adult murine dentate gyrus of the hippocampus

Publications:

Schneider J, Karpf J, Beckervordersandforth R (2019) Role of Astrocytes in the Neurogenic Niches. Methods Mol Biol 1938: 19-33. doi: 10.1007/978-1-4939-9068-9_2

Caroline Swoboda

Psychiatrische und Psychotherapeutische Klinik
AG Kornhuber

Supervisor

Project Title: Identification of biomarkers in depression